New small Xiao MG24 Sense board - can it run microPython?

No. It can be programmed with Arduino IDE, but it has been integrated with sensors (mic, 6-axis IMU sensor, etc), excellent for IoT labs and teaching materials. The board follows the pin-outs and size of Seeedstudio's boards of Xiao series.

Ref#1: Getting Started with Seeed Studio XIAO MG24 | Seeed Studio Wiki 

Specification:

Why? (Merits / Features)

• Powerful CPU: with a 32-bit RISC architecture of ARM-Cortex M33 of max 78MHz, supporting instructions of DSP and FPU floating points.
• Ultra low power consumption: RX current 4.6mA/TX current 5mA (0dBm), various sleep modes.
• Powerful AI
• Multi-wireless protocols: WiFi, BLE

PINOUT (Click the picture to enlarge it):

Tutorial / Lab #01: Software Installation / Preparation

 Lab Materials:

• Seeed Studio XIAO MG24 board
• PC Computer
• USB Type-C cable

Arduino IDE is the recommended programming tool by SeeedStudio, so it is highly suggested to complete the software installation.

  Lab Procedures:

1. Download and Install a stable version of Arduino IDE, according to your operating system (OS) in your computer: https://www.arduino.cc/en/software
2. Launch the Arduino IDE app.
3. Connect the Xiao MG24 board to your computer and install the board as follows: (choose) File  >  Preferences  > Add it in the "Additional Board manager URL" URL: https://siliconlabs.github.io/arduino/package_arduinosilabs_index.json
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  https://siliconlabs.github.io/arduino/package_arduinosilabs_index.json
  
  
4. Check the Board manager :  Tools  >  Board  >  Board Manager  >  Type MG24  and click "Install"
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•  You can find the board Xiao MG24 (Sense) as shown below:
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• Choose the corresponding COM port:  Tools  >  Port  (see the picture below)
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• You could then get the board info by clicking:  Tools  >  Get Board Info 
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5. Restart the Arduino IDE app.
6. Select back the board
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7. Choose